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DTSTAMP:20260711T213638Z
UID:238e4c01-5438-45db-8f57-28fd985a1ef8
DTSTART:20261026T090000Z
DTEND:20261028T170000Z
DESCRIPTION:## Overview\nThis workshop aims to present the basics of Comput
 er-Aided Drug Design (CADD)\, taking examples from different therapeutic a
 reas and introducing appropriate mostly freely accessible tools. Participa
 nts will learn to perform and analyze real-world cases of tridimensional b
 iomolecular visualization\, ligand-protein docking\, ligand-protein co-fol
 ding\, ligand-based virtual screening\, protein target prediction\, small-
 molecule property calculations and bioisosteric design. \n\nThroughout the
  course\, we will use powerful\, yet simple and intuitive professional too
 ls\, commonly employed in molecular modelling\, drug design\, and bio- and
  chemo-informatics. In-house original CADD technologies and resources deve
 loped at SIB\, combined with third-party software will be employed. The le
 ctures and practices will be conducted by the scientific developers of the
  SIB resources\, who will be available to discuss individual research need
 s of the participants.\n\n## Audience\nThis course is designed for PhD stu
 dents\, postdoctoral and other researchers in the life sciences from both 
 academia and industry who are interested in drug design. \n\n## Learning o
 utcomes\nAt the end of the course\, the participants are expected to:\n\n*
  **display** biomacromolecules in 3D\, **relate** ligand-protein complexes
  and **develop** high-quality images and interactive sessions with UCSF Ch
 imeraX\n* **execute** molecular docking with the [SwissDock](https://www.s
 wissdock.ch/) webtool and analyze interactions at the atomic level in Chim
 eraX\n* **execute** ligand-based screening on-line using [SwissSimilarity]
 (http://www.swisssimilarity.ch/)\n* **infer** the most probable protein ta
 rgets of bioactive small molecules with [SwissTargetPrediction](http://www
 .swisstargetprediction.ch/)\n* **compute** ADME\, physicochemical\, pharma
 cokinetic\, druglikeness and related properties of molecules with [SwissAD
 ME](https://www.swissadme.ch/) \n* **perform** bioisosteric design for an 
 educated selection of molecular replacements in the context of lead optimi
 zation or scaffold hopping using [SwissBioisostere](http://www.swissbioiso
 stere.ch/)\n*	**predict** structures of biomolecular complexes using co-fo
 lding tools such as AlphaFold and Boltz\n\n\n## Prerequisites\n##### Knowl
 edge / competencies\n*	Basic knowledge in biology\n*	Basic knowledge in ch
 emistry.\n\n\n\n##### Technical\nA Wi-Fi enabled laptop with two programs 
 installed: UCSF ChimeraX and a web browser (recent version of Firefox or C
 hrome). Please click [HERE](https://www.cgl.ucsf.edu/chimerax/download.htm
 l) to install the latest production release of UCSF ChimeraX. \nThere will
  be access to the eduroam and guest WiFi network. \n\n## Schedule - CET ti
 me zone\n\n**Tentative program**\n\n**Day 1** 9:15 - 17:15\n\n**Day 2** 9:
 15 - 17:15\n\n**Day 3** 9:15 - 17:15\n\n## Application\n\nThe registration
  fees for academics are **300 CHF** and **1500 CHF** for for-profit compan
 ies.\n\nYou will be informed by email of your registration confirmation. U
 pon reception of the confirmation email\, participants will be asked to co
 nfirm attendance by paying the fees within 5 days.\n\nApplications close o
 n *28/09/2026*. Deadline for free-of-charge cancellation is set to *28/09/
 2026*. Cancellation after this date will not be reimbursed. Please note th
 at participation in SIB courses is subject to our [general conditions](htt
 ps://www.sib.swiss/training/terms-and-conditions).\n\n## Venue and Time\nT
 his course will take place at the University of Bern.\n\n\nThe course will
  start at 9:15 CET and end around 17:15 CET.\n\n\nPrecise information will
  be provided to the registered participants in due time.\n\n\n## Additiona
 l information\nCoordination: Valeria Di Cola\, SIB Training Group.\n\nA **
 Certificate of Attendance** will be sent provided you were present at the 
 course\, whereas a **Certificate of Achievement** recommending 0.75 ECTS w
 ill be sent provided you passed the exam.\n\n\nYou are welcome to register
  to the SIB courses mailing list to be informed of all future courses and 
 workshops\, as well as all important deadlines using the form [here](https
 ://lists.sib.swiss/mailman/listinfo/courses).\n\n\nPlease note that partic
 ipation in SIB courses is subject to our [general conditions](http://www.s
 ib.swiss/training/terms-and-conditions).\n\n\nSIB abides by the [ELIXIR Co
 de of Conduct](https://elixir-europe.org/events/code-of-conduct). Particip
 ants of SIB courses are also required to abide by the same code.\n\n\nFor 
 more information\, please contact [training@sib.swiss](mailto://training@s
 ib.swiss).
SUMMARY:Computer-Aided Drug Design
URL;VALUE=URI:https://www.sib.swiss/training/course/20261026_CADDS
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