Belgium
Exploring protein structures: from analysis to prediction
Date: 25 - 26 November 2026
Duration: P1DT16H
Language of instruction: English
Understanding protein structure is key to unlocking biological function and interactions. This two-day course introduces the fundamental principles of protein structure analysis and prediction for researchers who are new to the field. You will learn how to explore, compare, and visualize protein structures and gain insights into modern prediction methods. The training also covers approaches for designing protein variants and studying protein-protein interactions, combining theory with extensive hands-on practice. On the first day, we combine short theoretical sessions with extensive hands-on exercises. On the second day, participants will apply these protein prediction tools to their research questions, with guided support.
Keywords: advanced bioinformatics, Artificial Inteligence
Venue: Ghent - VIB/UGent FSVM II, Technologiepark 75
City: Zwijnaarde
Country: Belgium
Postcode: 9052
Learning objectives:
- “Apply AlphaPulldown to conduct protein-protein interaction screens”
- “Design new stable proteins with web-based tools like PROSS or ProtFire”
- “Formulate a research question involving structural prediction and select appropriate tools (AlphaFold3 Boltz-1 Chai-1) to address it”
- “Predict 3D protein structures using AlphaFold2 on the VSC HPC and analyze the quality of the resulting models”
- “Search for structurally similar proteins using FoldSeek”
- “Set up and execute in silico site-directed mutagenesis experiments on the VSC HPC using tools like MutateX”
- “Visualize protein structures and compare homologous proteins using ChimeraX to interpret structural similarities and differences”
Organizer: VIB (https://ror.org/03xrhmk39)
Event types:
- Workshops and courses
Sponsors: Vlaams Supercomputer Centrum
Instructors: 
Alexander Botzki, Kenneth Verstraete, Jasper Zuallaert
Activity log
